Found: A protein that drives ageing without unleashing inflammation

Email Bluesky Facebook LinkedIn Reddit Whatsapp X Save article View saved research Researchers have found an enzyme that drives ageing in the body’s tissues 1 . Drugs that reduce the levels of this protein might one day combat the effects of ageing without impairing the body’s immune defences. Access options Access through your institution Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription $39.99 / 30 days cancel any time Learn more Subscribe to this journal Receive 51 print issues and online access $199.00 per year only $3.90 per issue Learn more Rent or buy this article Prices vary by article type $1.95 to $39.95 Learn more Prices may be subject to local taxes which are calculated during checkout doi: https://doi.org/10.1038/d41586-026-03638-3 References Kannangara, D. et al. Immunity https://doi.org/10.1016/j.immuni.2026.10.013 (2026). Article Google Scholar Download references Subjects Ageing Latest on: Ageing Bistable regulation of adipocyte heterogeneity governs thermogenesis Article 11 NOV 26 Can science make your dog live longer? Longevity craze comes to pets News 26 OCT 26 Worms live longer in cool conditions thanks to a muscle-derived molecule News & Views 21 OCT 26 Jobs Four PhD fellowships in AI-driven plant biology - University of Copenhagen Four PhD positions (NNF and MSCA) on knowledge graphs, single-cell stress networks and plant metabolic pathways. Deadline 31 Jan 2027. Frederiksberg Campus, University of Copenhagen, Denmark University of Copenhagen, Department of Plant and Environmental Sciences Strategic Scientist, Outstanding Youg Investigator, and Postdoctoral Positions at CIBCAS CIB invites distinguished Strategic Scientist, Outstanding Young Investigator, and Postdoctoral Research Fellow. Chengdu, Sichuan (CN) Chengdu Institute of Biology, Chinese Academy of Sciences State Key Laboratory of Quantitative Synthetic Biology Global Talent Wanted Applicants should meet the requirements for the National Science Fund for Excellent Young Scholars (overseas), please refer to the Part IV for details Shenzhen, Guangdong (CN) The State Key Laboratory of Quantitative Synthetic Biology Assistant Professor, Tenure Track, CHOP Division of Hematology Perelman School of Medicine at the University of Pennsylvania seek candidates for an Assistant Professor position in the tenure track. Philadelphia, Pennsylvania (US) University of Pennsylvania Bioinformatician – Long-Read Genomics, Pangenomics and Precision Medicine Talented bioinformatician with expertise in the analysis of long-read genomic and multi-omics sequencing data, genome assembly, and pangenomics. Doha (QA) Sidra Medicine Qatar